fight against obesity without surgeries, the possible side effects of medications and even changes in routine is the dream of many people who live with the condition, linked to diseases such as diabetes, cardiovascular problems, hypertension and cancer. The possibility of attacking specific fat deposits in a “liposuction” without cuts was presented by researchers from Columbia University, in the United States, who discovered that by applying nanotechnology to a material called P-G3, with a charge of positive chemical species, it’s possible inhibit visceral and body fat storage🇧🇷 The findings were published in two studies by the group in the scientific journals Nature Nanotechnology and Biomaterials🇧🇷
With the technique, the researchers used the liposuction concept of remodeling fat instead of simply destroying it. They observed that adipose tissue has expressive amounts of substances with a negatively charged extracellular matrix, which allows the maintenance of fat cells in the region, and concluded that this network could help to transport molecules with a positive charge. By injecting the nanomaterial into obese mice, the P-G3 quickly spread through the adipose tissue and deactivated the fat storage mechanism in fat cells🇧🇷 After that, the guinea pigs lost weight.
“Our approach is unique: part of pharmacological or surgical approaches. We use a technique that no one has ever used to treat obesity. I think this new strategy will open the door to healthier and safer fat reduction,” said Li Qiang, associate professor of pathology and cell biology, who led the study.
By inhibiting lipid storage, important process so that the fat cells do not grow in excess and the content overflowsthe mice had small, healthy adipose cells, comparable to those found in athletes🇧🇷
Experts believe that the method may even have application for aesthetic purposes. Just like Botoxthe nanomaterial could be injected into areas with subcutaneous fat.
“Now we can reduce fat in a depot-specific way – anywhere we want – and safely, without destroying fat cells. This is a major breakthrough in the treatment of obesity,” said Qiang.